Buy Depakote Online – epilepsy treatment medication

Trade name: Depakote.

Main ingredient: sodium valproate.

Group: anticonvulsants.

Product: in the form of tablets or capsules, including prolonged action.

Depakote Pharmacology

The active ingredient of this medication increases gamma-aminobutyric acid concentration in the brain postsynaptic receptors. It blocks potassium ion channels in the neurons cell membranes, which eliminates the undesired production of glutamic acid — an aliphatic amino acid — the key substance of epileptic seizures nature.

Drug does not have any serious hypnotic and sedative effects, and does not cause any respiratory center problems. It does not significantly increase blood pressure, heart rate, kidney function and temperature of the body.

Medical use Depakote

Focal or seizure epilepsy treatment, including the following types of seizures:

  • common and complex absence seizures;
  • tonic-clonic;
  • myoclonic;
  • atonic.

Focal epilepsy:

  • simple and complex seizures;
  • secondary generalized seizures.

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Before starting to take Depakote it’s necessary to consider the existence of others patient’s diseases, which may be exacerbated by using this medication.

Cautions when taking Depakote

If taking this medication on regular basis at least once in three months you should keep under control the bile pigment bilirubin level, platelet count and activity of some enzymes — tranaminazy and amylase.

Medication may cause risk of sudden bleeding and bruising. If any, immediately stop taking this medication.

The active ingredient of Depakote can cause liver and pancreas disfunction. In this case treatment should be done under control of these organs. The level of prothrombin also should be controlled.

Reduced concentration after taking the medication may cause danger in driving or operating dangerous machinery.

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Depakote: possible side effects and dosage

in Depakote.

Depakote is Anticonvulsant successfully used for the treatment of various epilepsy forms. Unlike the other similar drugs in the group it creates less sedative effects, and it also does not affect blood pressure and heart rate.

Depakote Side effects:

  • nausea, vomiting, constipation or diarrhea;
  • pancreatitis, hepatitis;
  • itching, skin rash;
  • consciousness disturbance, tremors;
  • disruption of the menstrual cycle;
  • blood cells concentration reduction: platelets, neutrophils, white blood cells         and hemoglobin;
  • increasing ammonium ions and creatinine level;
  • hair loss, weight gain.

Depakote dosage

The initial daily dose for adults is 600 mg. Every three days it shall be increased to 200 mg to find effective dosage.

Maximum dose is 1-2 grams per day.

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Depakote Instructional Video

in Depakote.

Depakote Instructional Video.

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The drug Depakote

Depakote is a drug for the treatment of epilepsy. Components of the drug increase the concentration of gamma-aminobutyric acid in the central nervous system. This leads to a decrease in excitability and prevents spasms in areas of the brain that are responsible for motor function. Depakote enhances the mood of patients and improves their mental state.

Indications for use

Depakote can help with the following diseases:

  • convulsive syndromes that occur in diseases of the brain;
  • violations and behavioral disorders, as the effects of epilepsy;
  • bipolar disorder or manic depressive psychosis;
  • Children’s teak or febrile convulsions;
  • epilepsy seizures (partial, focal, generalized) with different types of symptoms.

Side effects
When using Depakote, in rare cases there may be side effects that affect various organs of patient.

  • Central nervous system: shaking of arms or hands, change in mental status, mood, behavior, nystagmus, diplopia, incoordination, spots before the eyes. In very rare cases, there is dizziness, drowsiness, restlessness, anxiety and irritability.
  • Digestive system: diarrhea, loss of appetite, weak spasms in the stomach or abdominal pain, nausea and indigestion. There may be cases of constipation and pancreatitis.
  • The system of blood coagulation: bleeding time may increase, thrombocytopenia is possible.
  • The system of metabolism: may change the patient’s body weight (increase or decrease).
  • Gynecology: menstrual cycle can be broken.
  • If you have an allergy to the drug, this allergy can manifest itself a rash.

Should be aware that the side effects are very rare and their occurrence depends only on the characteristics of the individual patient. The drug Depakote has passed all the necessary tests and has the proper certifications.

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The use of Depakote

The drug Depakote is aimed at suppressing seizures of epilepsy and improving the patient’s condition.


Each patient requires an individual dosage regimen of the drug Depakote.

The initial dose for children weighing more than 25 kg and for adults is 10-15 mg per kilogram of weight per day. Then, gradually, at intervals of 3-4 days, the amount of medication is increased to reach 200 milligrams per day. These actions help to achieve the best clinical response. It is important to remember that the average daily norm should not exceed 30 mg / kg body weight.

The drug should be used during meals 2-3 times per day.

Depakote should be taken with caution by patients with the following diseases and disorders:

  • blood dyscrasia;
  • brain disease (organic);
  • hypoproteinemia;
  • liver disease in anamnesis;
  • kidney disease.

When taking the drug you should be cautious when doing work that requires high concentration, such as driving.

Buy Depakote online
The drug Depakote can relieve the symptoms and help to get rid of painful spasms that occur in epilepsy. It helps not only adults, but also the smallest patients.

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Depakote Contraindications

The most common contraindications to the use of the drug Depakote are:

  • violation of pancreatic function;
  • a variety of diseases of the liver;
  • diathesis of hemorrhagic type;
  • porphyria;
  • chronic or acute hepatitis;
  • sensitivity or intolerance to Depakote and its components.

Using during pregnancy and lactation

The drug Depakote can cause various congenital anomalies, so it is not recommended during pregnancy.

During breast-feeding from 1% to 10% of the drug contained in the plasma of patients can get into lactate. Therefore it is recommended to use Depakote only in cases of extreme necessity.

During the course of treatment, women in their childbearing years should take all measures to reliable contraception.

Application for violations of renal function or liver disease

At treatment of various liver diseases, the use of Depakote may increase the risk of side effects.
At illnesses of kidneys you should observe extreme caution.

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